INTUSSUSCEPTION IN INFANTS WITH SARS-COV-2 INFECTION
Аннотация
The new Corona virus disease 2019 (COVID-19) first presented in Wuhan, China. The virus was spread
throughout the world, causing a global health crisis. The COVID-19 pandemic poses a serious challenge to health
systems around the world. As one of the measures to prevent the spread of the virus, the Bulgarian government
has suspended the plan for scheduled operations, except for emergencies. However, in rare cases the disease might
be present with non-respiratory symptoms. The presentation of COVID-19 as a case of intussusception in children
is an atypical and rare phenomenon. Intussusception is the leading cause of intestinal obstruction in children under
4years of age. Viral infections are the associated etiology in most cases, SARS-CoV-2 thereby being a plausible
cause.
We present here a case of a 3-month-old male child who was admitted to hospital due, frequent vomiting,
food refusal, dehydration, recurrent severe abdominal pain and with currant jelly stool without fever.
Intussusception confirmed by ultrasound led to surgery. The child was tested for corona due to hospital admission
protocols during a pandemic. Surgical findings reported intussusception of the sygmoid colon, peritonitis, without
intestinal ischemia and mesenteric lymphoid hyperplasia. The COVID-19 infection was without respiratory
symptoms, and there was no need for the child to remain in department of pediatric surgery and was referred to a
special department for the treatment a COVID infection in children.
Some case reports introduced the presentation of COVID-19 as without respiratory symptoms in children.
Ubiquitous availability of corona virus and performing COVID-19 tests for children with intussusception can lead
to connection between them.
Литература
2.Shereen MA, Khan S, Kazmi A, Bashir N, Siddique R. COVID-19 infection: Origin, transmission, and characteristics of human coronaviruses. J Adv Res. 2020;24:91-98. Published 2020 Mar 16. doi:10.1016/j.jare.2020.03.005.
3.Zaim S, Chong JH, Sankaranarayanan V, Harky A. COVID-19 and Multiorgan Response. Curr Probl Cardiol. 2020;45(8):100618. doi:10.1016/j.cpcardiol.2020.100618.
4.Villapol S. Gastrointestinal symptoms associated with COVID-19: impact on the gut microbiome. Transl Res. 2020;226:57-69. doi:10.1016/j.trsl.2020.08.004.
5.Moazzam Z, Salim A, Ashraf A, Jehan F, Arshad M. Intussusception in an infant as a manifestation of COVID-19. J Pediatr Surg Case Rep. 2020;59:101533. doi:10.1016/j.epsc.2020.101533.
6.Athamnah MN, Masade S, Hamdallah H, et al. COVID-19 presenting as intussusception in infants: A case report with literature review. J Pediatr Surg Case
Rep. 2021;66:101779. doi:10.1016/j.epsc.2021.101779.
7.Jiang J., Jiang B., Parashar U., Nguyen T., Bines J., Patel M.M. Childhood intussusception: a literature review. PloS One. 2013;8:1–14. doi: 10.1371/journal.pone.0068482.
8.E.A. Edwards, N. Pigg, J. Courtier, et al. Intussusception: past, present and future,Pediatr Radiol, 47 (2017), pp. 1101-1108, 10.1007/s00247-017- 3878-x;.
9.Lucey BC, Stuhlfaut JW, Soto JA. Mesenteric lymph nodes seen at imaging: causes and significance. Radiographics. 2005 Mar-Apr;25(2):351-65. doi: 10.1148/rg.252045108. PMID: 15798054.
10.Navarro S., Driscoll B. Regeneration of the aging lung: a mini-review. Gerontology. 2017;63:270– 280. doi: 10.1159/000451081.
11.Dhochak N., Singhal T., Kabra S.K., Lodha R. Pathophysiology of COVID-19: why children fare better than adults? Indian J Pediatr. 2020;416 doi: 10.1007/s12098-020-03322-y.
12.Ong J.S.M., Tosoni A., Kim Y.J., Kissoon N., Murthy S. Coronavirus disease 2019 in critically ill children: a narrative review of the literature. PediatrCrit Care Med. 2020:1–5. doi: 10.1097/PCC.0000000000002376.
13.Ni W, Yang X, Yang D, et al. Role of angiotensin-converting enzyme 2 (ACE2) in COVID19. Crit Care. 2020;24(1):422. Published 2020 Jul 13. doi:10.1186/s13054-020-03120-0.
14.Zhang X, Yu Y, Zhang C, et al. Mechanism of SARS-CoV-2 Invasion into the Liver and Hepatic Injury in Patients with COVID-19. Mediterr J Hematol Infect Dis. 2022;14(1):e2022003. Published 2022 Jan 1. doi:10.4084/MJHID.2022.003.
15.Cui X., Zhang T., Zheng J., Zhang J., Si P., Xu Y. Children with coronavirus disease 2019 (COVID‐ 19): a review of demographic, clinical, laboratory and imaging features in 2,597 pediatric patients. J Med Virol. 2020;2019 doi: 10.1002/jmv.26023. 0–3.
16.Lucey BC, Stuhlfaut JW, Soto JA. Mesenteric lymph nodes seen at imaging: causes and significance. Radiographics 2005;25:351–65.
17.Shahfar Khan, Luke Hartman, Youck Jen Siu Navarro, Connie J. Rossini, Catherine Burdett, Christopher Pennell,Pediatric Covid-19 mesenteric lymphoid hyperplasia associated intussusception: A case report and literature review, Journal of Pediatric Surgery Case Reports, Volume 73, 2021, 101988, ISSN 2213-5766, https://doi.org/10.1016/j.epsc.2021.101988.
18.Gao Y, Xi H, Chen L. Emergency surgery in suspected COVID-19 patients with acute abdomen: case series and perspectives. Ann Surg 2020;272:e38– 9.
19.Petar Stamov, Sylvia Stamova, Dora Vasileva. GASTROINTESTINAL FORM OF COVID-19 MIMICRING LIKE INTUSSUSCEPTION SYMPTOMS. WORLD CHILDREN CONFERENCEII May 21-23, 2021 Nicosia / Turkish Republic of Northern Cyprus Özay Günsel Children University Proceedings Book Volume-I IKSAD GLOBAL PUBLISHING HOUSE ISBN: 978-605-70554-8-4 www.worldchildrenconference.or, p.219-221.
20.Khan S, Hartman L, Navarro YJS, Rossini CJ, Burdett C, Pennell C. Pediatric Covid-19 mesenteric lymphoid hyperplasia associated intussusception: A case report and literature review. J Pediatr Surg Case Rep. 2021;73:101988. doi:10.1016/j.epsc.2021.101988.
CC BY-ND
Эта лицензия позволяет свободно распространять произведение, как на коммерческой, так некоммерческой основе, при этом работа должна оставаться неизменной и обязательно должно указываться авторство.
