SELECTION OF A SOLVENT FOR SPECTROPHOTOMETRIC ANALYSIS OF A THREE-COMPONENT MEDICINAL MIXTURE

  • L. Kotlova FSBEI HE TyumGMU of the Ministry of Health of Russia
  • T. Cokova Tyumen State Medical University (FGBOU VO TyumGMU of the Ministry of Health of Russia)
Keywords: spectrophotometry, absorption spectra, drug mixtures

Abstract

The aim of the study was to select a solvent for spectrophotometric analysis of a three-component drug mixture containing acetylsalicylic acid, paracetamol, and caffeine without separating the components. The spectra were studied in acidic and alkaline media at concentrations corresponding to the composition of Citramon-S tablets. We have proposed a solvent: ethyl alcohol 98% - 0.01 mol / l solution of hydrochloric acid in a ratio of 1:10.

Author Biographies

L. Kotlova , FSBEI HE TyumGMU of the Ministry of Health of Russia

Candidate of Pharmaceutical Sciences, Associate Professor of the Department of Chemistry

T. Cokova , Tyumen State Medical University (FGBOU VO TyumGMU of the Ministry of Health of Russia)

Candidate of Biological Sciences, Associate Professor of the Department of Medical Informatics and Biological Physics with the UNESCO Bioethics Network Section

References

1. OFS 1.2.1.0003.15 Spektrofotometriya v ultrafioletovoj i vidimoj oblastyah.
2. FS 2.1.0006.15 Acetilsalicilovaya kislota
3. FS 2.1.0116.18 Kofein
4. FS 2.1.0154.18 Paracetamol
5. Cokova, T.N. Metod proizvodnoj UFspektrofotometrii opredeleniya koncentracii lekarstvennogo preparata v smesyah / Cokova T.N., Kotlova L.I., Osipova A.V. // Mezhdunarodnyj zhurnal prikladnyh i fundamentalnyh issledovanij. - M. «Akademiya estestvoznaniya». - 2015. - №11 (chast 5) - S. 694-698.
Published
2021-07-10
How to Cite
Kotlova , L., and T. Cokova. 2021. “SELECTION OF A SOLVENT FOR SPECTROPHOTOMETRIC ANALYSIS OF A THREE-COMPONENT MEDICINAL MIXTURE”. EurasianUnionScientists, July, 33-36. https://bio-med.euroasia-science.ru/index.php/Euroasia/article/view/737.
Issue
EURASIAN UNION OF SCIENTISTS. SERIES: MEDICAL, BIOLOGICAL AND CHEMICAL SCIENCES. VOLUME 1 №6 (87) (2021)
Section
Article

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