CHANGES IN THE WALL OF THE CAROTID ARTERIES IN DIFFERENT AGE GROUPS
Abstract
The results of studies of the walls of the carotid arteries from 106 deceased aged 19 to 95 years without cardiovascular diseases detected during life or at autopsy are presented. Two study groups were identified: the younger (n=56, average age 36.57±7.77 years) and the older (n=50, average age 71.04±13.45 years) A comparative morphometric analysis of macro - and microscopic parameters was performed: vessel diameter, wall thickness, specific volume of smooth muscle cells, the coefficient of elastic membranes, the coefficient of Vogenworth and Kernogan. Statistically significant differences between the groups were established. In the older age group, the diameter of the arteries increases, their inner and medial layers thicken, the cellular composition and content of the extracellular matrix changes, hemodynamic vascular disorders occur. In addition, changes in the arterial wall, characteristic of the older group, in some cases can be detected in the younger age group.
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